toxicology
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Local Anesthetic Systemic Toxicity – Is Fat The New “Wonder Drug?”
Image Credit: Photo by NIH: https://flic.kr/p/nQg4F7 Author: Jonathan Morgan, MSIVLake Erie College of Osteopathic Medicine-Bradenton The provision of local and regional anesthesia is a core part of emergency medicine. Toxicity as a result of the administration of local anesthetics is exceedingly rare, but it does occur, and may even be more common than malignant hyperthermia.[1] […] -
Peds Tox Talk: Liquid Nicotine
Photo by Lindsay Fox Author: Ashley Grigsby, DO PGY-1Indiana University Emergency Medicine/Pediatrics Originally Published: Modern Resident, June/July 2015 Nicotine toxicity is a well-described clinical entity that often occurs in children who accidentally ingest cigarette buds or nicotine patches. However, a new form of nicotine has the potential to cause serious clinical symptoms, including death. E-cigarettes […] -
Treatment of Diphenhydramine Cardiotoxicity
Source: Flickr Author: Teng Lu, MDEmergency Medicine ResidentStanford-Kaiser Emergency Medicine Residency This post was peer reviewed.Click to learn more. CaseA 16 year old girl was brought in by family for ingestion of an unknown amount of diphenhydramine (Benadryl®) in a suicide attempt. Initial vitals were remarkable for sinus tachycardia at a rate of 120. Her […] -
Tox Talks: Drug Induced Noncardiogenic Pulmonary Edema
Author: Ashley Grigsby, DO, Indiana University Noncardiogenic pulmonary edema (NCPE) is a clinical entity consisting of alveolar fluid accumulation without evidence of cardiac cause.[1] Although there are many non-toxicologic causes of NCPE, both opiate overdose and salicylate toxicity are known to cause NCPE and should be part of one’s differential diagnoses. Opiate overdose induced NCPE […] -
‘Tis the Season to Investigate Holiday Plant Myths
Orignially Published: Modern Resident, Dec/Jan 2012 Original Authors: Christopher DeClue, MS1Veronica Tucci, MD JDMichael Omori, MD FACEPUniversity of South Florida Emergency Medicine Submitted by: Rachel Engle, DO Communications Committee Chair Contrary to popular belief, the poinsettia (Euphorbia pulcherrima) is not a toxic plant. This misconception began as an urban legend dating back to 1919 when […] -
Tox Talks
Originally Published: Modern Resident, Dec/Jan 2010 Submitted by: Saadiyah Bilal, Publications Committee, Co-Chair Iron toxicity remains a common toxidrome in the emergency department and is the leading cause of pediatric overdose death under age 6. Its antidote, defuroxamine, was recently designated by the Antidote Summit Authorship Group (Ann Emerg Med, Sept. 2009) as a medicine […] -
Tox Talks: Toxic Alcohols
Originally Published: Modern Resident, Oct/Nov 2010 Original Author: Neal Shelley, MD Georgetown/Washington Hospital Center Emergency Medicine Submitted by: Saadiyah Bilal, Publications Committee, Co-Chair Just like ethanol, ethylene glycol and methanol cause inebriation and are often ingested by a desperate alcoholic or as a suicide attempt. Whereas ethanol is preferentially metabolized by alcohol dehydrogenase to […] -
Board Review: Methadone Intoxication
Originally Published: Modern Resident, Jun/Jul 2010 Original Author: Dana Kindermann, MD Georgetown-Washington Hospital Center Dept. of Emergency Medicine Submitted by: Saadiyah Bilal, Publications Committee, Co-Chair Case history: 56 y/o male BIBA, found in apartment by roommate with altered mental status x 24h, found lying in feces. Patient (pt) with multiple substance abuse related admissions and […]
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